Product/Service Material

eGuide for Off-Target Screening via the Retrogenix® Platform

Toxicity due to cross-reactivity or "off-target" binding is a serious cause for concern in drug development. This eGuide brings together all the information you need on how the Retrogenix^® platform can be leveraged to screen for specificity in vitro against a physiologically relevant human protein library from early-phase discovery onwards, to aid candidate selection, downstream study design, and IND approval.

Test molecules descend towards receptors on the surface of reverse transfected human cells grown over expression vectors.

This eGuide provides a breakdown of:

Guidance on screening deliverables
Screening facts to support decision-making
The human protein library and screenable modalities
Screening workflow and processes
Next steps on screening via the Retrogenix^® platform

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